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Women with polycystic ovary syndrome (PCOS) are up to 4 times more likely to develop type 2 diabetes

Women with polycystic ovary syndrome (PCOS) are up to 4 times more likely to develop type 2 diabetes compared to women without PCOS. This is because women with PCOS often have insulin resistance and high glucose levels, both are key features for developing type 2 diabetes.

This research aims to identify whether breaking up long periods of sitting can help lower glucose and insulin levels in women with PCOS to ultimately decrease the future risk of developing type 2 diabetes.

Who can participate?

To participate in this trial, you must:

  • be aged 18–45 years
  • have polycystic ovary syndrome (PCOS)
  • live in Melbourne.

Enquire about participating in this study

What’s involved?

This study aims to test the acute effect of breaking up time spent sitting on glucose and insulin levels. We are also aiming to test whether breaking up sitting time can also lower testosterone and sex hormone-binding globulin (SHBG) levels.

Participants will be required to:

  • Undergo a blood test and/or an ultrasound of the ovaries to confirm PCOS (for screening purposes only).
  • Attend 3 visits: 1 familiarisation visit (2 hrs) and 2 x testing study visits (4 hrs each) over a 3 week period.
  • Provide blood samples at regular intervals (by means of intravenous catheter) during the experimental visits.
  • Wear physical activity and continuous blood glucose monitors for a 5-day period on two occasions.
  • Keep a record of your food and drink intake over a 24 hour period on two occasions.

If you are interested in participating or would like further information, please contact:

Elly Fletcher
T: +61 3 8532 1853
E: PCOS-BREAKS@baker.edu.au

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With the rising number of Australians affected by diabetes, heart disease and stroke, the need for research is more critical than ever.

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