Laboratory
Molecular Metabolism and Ageing
Sarah Jenkinson is a PhD candidate at the Baker Heart and Diabetes Institute, where her research investigates how mitochondrial dysfunction in the heart contributes to systemic metabolic disease. Her work focuses on understanding how mitochondrial DNA instability activates cellular stress pathways and alters the cardiac secretome, driving communication between the heart and peripheral organs such as the liver.
By combining tissue-specific mouse models with proteomics, molecular biology and metabolic phenotyping, Sarah aims to identify novel mechanisms linking cardiac mitochondrial dysfunction to metabolic complications in heart failure. Her research seeks to uncover new biomarkers and therapeutic targets that improve the diagnosis and treatment of heart failure and its systemic consequences.
Achievements
- Monash Graduate Research Scholarship (2026–2029)
- Baker Institute Bright Sparks Scholarship (2026–2029)
