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Project title: The long-term effects of a peer-led lifestyle intervention program on diabetes progression and cardiovascular risk: the Kerala Diabetes Prevention Program

This NHMRC-funded research examines the long-term effects of a peer-led lifestyle intervention program, the Kerala Diabetes Prevention Program (K-DPP), on diabetes progression and cardiovascular risk. This project involves the 8-year follow-up study of the program which has been implemented over a 12-month period in two districts within the state of Kerala, India. The project’s implementation is in collaboration between the Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) in Trivandrum, Kerala and the Baker Heart and Diabetes Institute, Melbourne, Australia.

The overall aim of this project is to evaluate the long-term effects of the K-DPP. The objectives are:

  • To measure the program effectiveness of K-DPP at 8 years from the implementation stage.
  • To undertake an economic evaluation of K-DPP to measure the long-term value and return on investment.
  • To evaluate community engagement and program sustainability of K-DPP groups and related community activities after 8 years.

This research has extensive data on behavioural/lifestyle, psychosocial, medical history and family history of disease, health service utilisation, anthropometric and biochemical measures, retinal vasculature, and ECG measures for middle-aged adults at elevated risk of diabetes at baseline. The data was collected at baseline, 12 months, 24 months and now at 8 years.

This project welcomes all Honours, Masters, and PhD students.

Selected publications

  1. Cluster randomised controlled trial of a peer-led lifestyle intervention program: study protocol for the Kerala diabetes prevention program
    BMC Public Health 2013 Nov 4; 13:1035
  2. Cultural adaptation of a peer-led lifestyle intervention program for diabetes prevention in India: the Kerala diabetes prevention program (K-DPP)
    BMC Public Health 2018 Jan 4;17(1):974
  3. A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program
    PLoS Med. 2018 Jun 6;15(6): e1002575
  4. A group-based lifestyle intervention for diabetes prevention in low- and middle-income country: implementation evaluation of the Kerala Diabetes Prevention Program
    Implement Sci. 2018 Jul 18;13(1):97
  5. Cost-effectiveness of a lifestyle intervention in high-risk individuals for diabetes in a low- and middle-income setting: trial-based analysis of the Kerala Diabetes Prevention Program
    BMC Med. 2020 Sep 4;18(1):251

For more information, contact Brian Oldenburg.

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