The Baker Institute is committed to scientific excellence and our ‘2016 Best of Baker Awards’ recognise outstanding research achievement based on scientific publications. They demonstrate areas where scientific discoveries are likely to have significant impact in health and medical research.
Among the findings, the papers detail:
- a new therapeutic strategy to treat a common, globally-recognised form of heart failure
- development of a gene therapy that could save millions of people from muscle-wasting disease
- a novel technology for the rapid, non-invasive diagnosis and effective, bleeding-free treatment of blood clots
- how fats in the bloodstream could predict the risk of heart disease in people with diabetes.
Our focus now is on translating this research to develop new drugs and devices, to inform policy, to develop best-practice prevention and treatment guidelines, and to facilitate education programs for healthcare professionals.
This is how our research is making a difference to the health of Australians, and people around the world.
- Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice (Basic Science)
- A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (Clinical / Epidemiology)
- Plasma lipidomic profiles improve on traditional risk factors for the prediction of cardiovascular events in type 2 diabetes mellitus (Clinical / Epidemiology)
- Thrombus-targeted theranostic microbubbles: a new technology towards concurrent rapid ultrasound diagnosis and bleeding-free fibrinolytic treatment of thrombosis (Basic Science)
- Differential effects of IL6 and activin A in the development of cancer-associated cachexia
- Age-specific trends from 2000–2011 in all-cause and cause-specific mortality in type 1 and type 2 diabetes
- Effect of aldosterone antagonism on exercise tolerance in heart failure with preserved ejection fraction
- Contribution of orexin to the neurogenic hypertension in BPH/2J mice
- Cytomegalovirus restructures lipid rafts via a US28/CDC42-mediated pathway, enhancing cholesterol efflux from host cells
- The effect of treatment of obstructive sleep apnea on glycemic control in type 2 diabetes
- Set7 mediated interactions regulate transcriptional networks in embryonic stem cells
- Alcohol and atrial fibrillation