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Diabetes and Vascular Medicine

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Laboratory head

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Latest Achievements

Importance of insulin resistance in type 1 diabetes and role of adjunct metformin, including the REMOVAL trial, formulae and an online calculator to estimate insulin resistance in type 1 diabetes

Quantitative and qualitative changes in lipoproteins and of glucose fluctuations in promoting diabetes and its complications

Development of a free online calculator to estimate sight-threatening diabetic retinopathy risk and fenofibrate benefit

Awareness of high cardiometabolic and eye damage risk in Indigenous Australians with diabetes, with eye screening training is now offered to diabetes educators

Personalising eye screening intervals and a free online calculator to optimise screening for youth with type 1 diabetes

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Professor Alicia Josephine Jenkins Laboratory Head
We are interested in improving the prediction and prevention of diabetes complications and cardiovascular disease and in the use of technology in healthcare, with equitable access for all who may benefit.


PhD students

James Wang

Affiliates and Collaborators

Dr Laima Brazionis Professor Jian-Xing Ma Chris Ryan

Visiting researchers

Alfrida Ruden Moa Seger Asher Yeung


About the Diabetes and Vascular Medicine laboratory

The Diabetes and Vascular Medicine lab is interested in the prediction and prevention of the complications of type 1 diabetes, type 2 diabetes and cardiovascular disease, and in the use of technology in healthcare.

The multidisciplinary team relocated to the Baker Heart and Diabetes Institute in 2023, after 10 years at the University of Sydney and 12 years at the University of Melbourne. With and for people living with or at risk of diabetes or cardiovascular disease, the team undertakes clinical (people-based) research and laboratory-based studies. They have an extensive, valued national and international network of collaborators.

The team has a biomarker laboratory with a wide range of clinical, biochemical and molecular tools that can be applied to their own research studies and are available for other researchers to use and learn.

Clinical trials include the FAME-1 Eye trial which is testing a once daily tablet of fenofibrate in adults with type 1 diabetes and early to moderate diabetic eye damage (retinopathy) to see if it can protect the eyes. There are a series of insulin pump and glucose sensor trials. Collaborative cohort studies include major international type 1 diabetes groups the DCCT/EDIC and FinnDiane. Biomarkers which may predict health outcomes or response to treatment are being conducted in these trials and cohorts and other completed trials such as the FIELD trial (of fenofibrate in Type 2 diabetes) and the REMOVAL trial (of adjunct metformin in adults with type 1 diabetes).

Building and learning from the next generation of biomedical researchers is key so the team includes clinical and science trainees from undergraduate to postgraduate level.

Lab members also serve the profession and community via membership of grant review panels and advisory boards, conference conduct, editorial roles and guideline developing groups. They are available as speakers for community groups and are actively engaged with humanitarian aid organisations.

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With the rising number of Australians affected by diabetes, heart disease and stroke, the need for research is more critical than ever.

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