Dr Donggyu Rim
BBiomedSci(Hon) | PhD, Monash University

I am a neurophysiologist specialising in the study of autonomic networks in the brain and their alterations in both health and disease. My research aims to uncover how these networks influence autonomic outflow to the heart and other organs, with the goal of improving our understanding and treatment of various conditions. By investigating these mechanisms, I hope to contribute to better diagnostic and therapeutic strategies for autonomic dysfunctions.
My current research targets the central autonomic network, focusing on key brain regions such as the rostral ventrolateral medulla, insula, cingulate cortex, and prefrontal cortex. I employ microneurography to measure sympathetic nerve activity, combined with functional magnetic resonance imaging (fMRI) to explore novel brain regions involved in autonomic regulation. This innovative approach allows us to directly measure nerve activity and correlate it with brain imaging data, providing a comprehensive view of how autonomic signals are generated and modulated.
One of my key projects focuses on autonomic dysfunction in long Covid patients with chronic fatigue syndrome. This work involves detailed analysis of how the autonomic nervous system is disrupted in these patients, aiming to identify specific brain regions and pathways that contribute to their symptoms. By understanding these mechanisms, we hope to develop targeted interventions to alleviate their condition.
I collaborate with researchers specialising in transcranial magnetic stimulation (TMS) to investigate the control of sympathetic outflow and identify neuronal populations excited by TMS. Additionally, I work with brain imaging researchers to find novel imaging biomarkers for autonomic nerve activity in both health and disease. Our multidisciplinary team includes neuroscientists, cardiologists, and exercise physiologists, and operates within the Baker Heart and Diabetes Institute, Australia's leading heart and diabetes research facility.
During my PhD, I conducted a study with hypertensive patients, elucidating the structural changes in the brain associated with sympathetic nerve activity. This work has provided valuable insights into how hypertension affects brain structure and function, further informing my current research.