Associate Professor Peter Meikle
Associate Professor Peter Meikle is a NHMRC Senior Research Fellow. He leads the Obesity and Diabetes Program and is Head of the Metabolomics Laboratory. He is Editor in Chief of the Journal Metabolites and holds affiliate positions at the University of Melbourne, Monash University and the NHMRC Clinical Trials Centre, University of Sydney.
Alterations in metabolism underpin many chronic diseases including obesity, type 2 diabetes, cardiovascular disease and age related dementia. While some metabolic pathways are well characterised, their dysregulation resulting from environmental and genetic influences are less well understood, particularly in a setting of chronic disease.
The Metabolomics Laboratory uses state of the art tandem mass spectrometry to obtain metabolic profiles from cell and animal models in addition to clinically relevant human samples. This approach is providing an improved understanding of disease mechanisms leading to new biomarkers for improved diagnosis and risk assessment as well as new therapeutic strategies in the areas of obesity, diabetes and cardiovascular disease.