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Dr Austin Lai

PhD, RMIT University | BSc(Hons)

Austin is a postdoctoral researcher in the Mechanobiology and Microfluidics lab at the Baker Heart and Diabetes Institute and is working on determining how the mechanosensitive ion channels such as Piezo1 contributes to endothelial physiology, vascular ageing, and cardiovascular disease.

He completed his PhD at RMIT University in which he studied how endothelial cells and mechanosensitive ion channels respond to haemodynamic forces, such as shear stress, and how these responses are influenced in aged blood vessels. 

The main interest of his research currently includes identifying downstream mechanobiological pathways involved in different cardiovascular pathology such as arterial stiffness and cardiac arrhythmia. His research takes advantage of microfluidic technology resembling the physiology of blood vessels and uses these bioengineered models to study endothelial mechanobiology. His research aims to provide insight into the underlying mechanisms of arterial stiffness caused by vascular ageing and identify suitable targets as therapeutic intervention for cardiovascular diseases.

Achievements

  • The Medical Advances Without Animals Trust (MAWA) Fellowship (2025–2026)
  • Cardiac Biology and Disease Program EMCR Grant (2024)
  • Australian Government Research Training Program Scholarship (2019–2022)

Awards

  • Alfred Research Week Scientific Abstract, Baker Heart and Diabetes Institute Prize (2024)
  • Paul Korner Medal, Baker Institute (2023)

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