I am a Master of Biotechnology student at the University of Melbourne, specialising in the intersection of epigenetics, molecular biology, and vascular health. My research focuses on understanding how epigenetic modifications, particularly DNA methylation, influence disease progression in cardiovascular and metabolic disorders. By investigating the early-life epigenetic signatures of key biomarkers, I aim to contribute to the development of personalised medical approaches for preventing and managing chronic diseases like diabetes and heart disease.

Currently, I am involved in a project that validates the methylation signatures of three biomarkers — FRAS1, CACNA1E, and KATNAL1 — identified in the DNA methylation analysis of cord-blood samples. Using Human Umbilical Vein Endothelial Cells (HUVEC) as a model, I investigate how these epigenetic changes affect endothelial function, which plays a critical role in vascular health. I employ advanced molecular biology techniques such as bisulphite sequencing, methylation-specific PCR, and bioinformatics analysis to map the epigenetic landscape of these biomarkers and uncover their potential role in disease progression.

My research not only provides crucial insights into the molecular mechanisms underlying vascular and metabolic diseases but also fits into the broader goal of developing targeted interventions for chronic disease management. Collaborating with researchers at the Baker Institute and other leading institutions, I am driven by my passion for uncovering the molecular drivers of disease and advancing the field of epigenetic therapeutics. In the long term, I hope my work will lead to earlier diagnoses, personalised treatments, and improved outcomes for patients with cardiovascular and metabolic diseases.