Yow Keat is a Group Leader and Baker-La Trobe Senior Research Fellow in the Metabolomics laboratory, where he currently leads the Cardiometabolic Lipidomics and Therapeutics Theme. His research utilises lipidomics, molecular biology and imaging techniques to understand cardiovascular disease using preclinical models. This ultimately is aimed at development of innovative lipid modulating therapies to treat cardiovascular and other chronic diseases.

His research has resulted in 21 career publications (~2100 citations, h-index 14) including ones in top journals such as Nature Communications, Cell Reports and Nature Cardiovascular Research. He has attracted ~$2.5 million in research funding, and the quality of his work has been recognised via publication (2015; 2023 — International Society for Heart Research) and presentation awards. In 2023, Yow Keat was awarded by the Baker Institute as an Emerging Leader in heart and diabetes research via the Sir Laurence Muir Prize.

Yow Keat was awarded his PhD in Medicine (Monash University, 2018), receiving the Paul Korner Medal for Outstanding Achievement. During his PhD, he demonstrated distinctive lipid profiles in the heart and circulation following exercise vs heart failure/disease, and how modulating different lipid species in the heart could affect cardiac health. His postdoctoral research further focused on the role of specific lipids in cardioprotection and heart disease, whether the manipulation of these lipids can serve as new therapies for heart failure and how changes to the heart can affect systemic change to lipids in other tissues.