Dr Louise Segan is a Cardiologist and Electrophysiologist and Clinical Electrophysiology researcher whose work focuses on improving outcomes for patients with atrial fibrillation and heart failure. Dr Segan’s research explores how cardiac rhythm disorders interact with structural heart disease, with a particular interest in identifying patients whose heart function may recover with targeted rhythm control strategies such as catheter ablation. By combining advanced cardiac imaging, clinical trials and translational research, Dr Segan’s work aims to better understand the mechanisms of atrial fibrillation-related cardiomyopathy and to refine treatment strategies that improve both cardiac function and quality of life for patients.

Dr Segan completed her PhD investigating outcomes of catheter ablation in patients with AF and left ventricular systolic dysfunction. Her research has contributed to landmark clinical trials examining the role of rhythm control in cardiomyopathy, including strategies exploring how myocardial fibrosis detected on cardiac MRI influences recovery of cardiac function following AF ablation. She works closely with multidisciplinary collaborators and teams across electrophysiology, cardiac imaging and heart failure research to translate mechanistic insights into enhancing patient care.

As a research fellow in clinical electrophysiology at the Baker Heart and Diabetes Institute, Dr Segan continues to investigate predictors of cardiac recovery and treatment response in arrhythmia-mediated cardiomyopathy. Dr Segan’s broader goal is to develop more personalised treatment approaches for patients with atrial fibrillation, ensuring that therapies such as catheter ablation are targeted and accessible to those most likely to benefit.