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Preclinical Disease and Prevention

Reducing the risk of complications from cardio-metabolic disease.

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Laboratory head

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Latest Achievements

European Society of Cardiology Heart Failure, Late breaking science award (2017)

European Society of Cardiology, Late breaking science award (2015)

European Society of Cardiology Heart Failure, Late breaking science award (2014)

American Heart Association, Late breaking trial (2014)

American Heart Association, Best research paper (2013)

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Associate Professor Melinda Carrington Laboratory Head
Focused on supporting individuals to reduce their risk of complications from cardiometabolic disease.


Research staff

Ms Asmita Dalal Ms Carla Duarte Ms Batsheva Greenbaum Dr Tilahun Nigatu Haregu Ms Sally Bronwyn Kay Ms Swetha Raghavan


About Preclinical Disease and Prevention

The Preclinical Disease and Prevention unit is devoted to helping people identify and address their risk of developing or managing two of Australia’s most prevalent chronic diseases — cardiovascular disease and diabetes. The research of the Preclinical Disease and Prevention unit is predominantly undertaken in community settings with a focus on higher risk individuals.

The Preclinical Disease and Prevention unit conducts rigorous, multi-disciplinary clinical trial research to demonstrate the benefits of nurse-facilitated models of care. Integral to this work is the establishment of nurse-led clinics to promote health behaviour change and implement gold standard care to enhance management.

The Unit also develop practical electronic resources for use by individuals and health care professionals that optimise cardiovascular disease management in community and clinical settings.

We collaborate with eminent cardiologists, endocrinologists, leading GP academics and Aboriginal health researchers. These partnerships, combined with the Unit’s expert team of research fellows, clinical researchers, data management and support staff enable the unit to deliver personalised care that targets risk and protective factors to help disadvantaged individuals.

Research focus

  • Multi-site, randomised controlled trials of risk factor management and health and lifestyle interventions for the prevention and management of cardiometabolic disease.
  • Establishing the evidence for nurse-led models of care.
  • Risk detection and surveillance of traditional and novel risk indicators.
  • Sleep.
  • Digital eHealth applications for patients living with chronic disease.
  • Mass data analyses of primary care management of cardiometabolic risk.
  • Pregnancy related cardiovascular disease risk.

Support us

With the rising number of Australians affected by diabetes, heart disease and stroke, the need for research is more critical than ever.

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