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The Prospective Athlete Heart Study: elucidating genetic determinants of cardiac remodelling using endurance exercise as an environmental stress

Leader: Andre La Gerche

Pro@Heart is an international prospective longitudinal study which will detail the evolution of exercise-induced cardiac remodelling ('athlete's heart') amongst elite junior endurance athletes. The study will quantify individual variance in the extent and rate of development of athlete's heart, identify its genetic determinants and assess clinical outcomes. Pro@Heart will be conducted over 25 years thus enabling the long-term health benefits of endurance sports training to be assessed using robust clinical end-points.

We are currently recruiting participants for a clinical trial related to this project.